Sublingual epithelial cells have properties which are very
useful for general body analysis.
They
have aerobic metabolism which means they have
mitochondria, the powerhouse of the cell. They use a lot of
oxygen and make ATP, the fuel that drives all cells. They
contain the magnesium and other elements needed to drive
mitochondrial function.
Sublingual epithelial cells
turnover very quickly, every
few days, which means they have a high metabolism and
reflect current status.
As a matter of fact the entire coating
and lining of the gastro-intestinal system does the same
thing.
Sublingual cells are non-cornified which means they are
viable, stable cells; they do not look like brittle cornflakes.
They are easily accessible and require minimal cell
manipulation and prep. You can transport them with no
loss of information. Once fixed, the cell smear is good for
analysis for many years.
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